Genome Biology, 2021. AMULET: a novel read count-based method for effective multiplet detection from single nucleus ATAC-seq data

Authors: A. Thibodeau, A. Eroglu, C. S. McGinnis, Nathan Lawlor, D. Nehar-Belaid, R. Kursawe, R. Marches, D. N. Conrad, G. A. Kuchel, Z. J. Gartner, J. Banchereau, M. L. Stitzel, A. E. Cicek & D. Ucar


Nature Communications, 2021. Tet2 Controls the Responses of β cells to Inflammation in Autoimmune Diabetes

Authors: J. Rui, S. Deng, A. L. Perdigoto, G. Ponath, R. Kursawe, N. Lawlor, T. Sumida, M. Levine-Ritterman, M. L. Stitzel, D. Pitt, J. Lu, K. C. Herold


Frontiers in Immunology, 2021. Single Cell Analysis of Blood Mononuclear Cells Stimulated Through Either LPS or Anti-CD3 and Anti-CD28

Authors: N. Lawlor, D. Nehar-Belaid, J. D.S. Grassmann, M. Stoeckius, P. Smibert, M. L. Stitzel, V. Pascual, J. Banchereau, A. Williams, D. Ucar


Bioinformatics, 2020. V-SVA: an R Shiny application for detecting and annotating hidden sources of variation in single cell RNA-seq data

Authors: N. Lawlor, E. J. Marquez, D. Lee, and D. Ucar


Molecular Metabolism, 2019. (Epi)genomic heterogeneity of pancreatic islet function and failure in type 2 diabetes

Authors: N. Lawlor, M. L. Stitzel


Cell Reports, 2019. Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function

Authors: N. Lawlor, E. J. Marquez, P. Orchard, N. Narisu, M. S. Shamim, A. Thibodeau, A. Varshney, R. Kursawe, M. R. Erdos, M. Kanke, H. Gu, E. Pak, A. Dutra, S. Russell, X. Li, E. Piecuch, O. Luo, P. S. Chines, C. Fuchbserger, P. Sethupathy, A. P. Aiden, Y. Ruan, E. L. Aiden, F. S. Collins, D. Ucar, S. C.J. Parker, and M. L. Stitzel


Scientific Reports, 2018. Detection of correlated hidden factors from single cell transcriptomes using Iteratively Adjusted-SVA (IA-SVA)

Authors: D. Lee, A. Cheng, N. Lawlor, M. Bolisetty, and D. Ucar


Nucleic Acids Research, 2018. BiFET: A Bias-free Transcription Factor Footprint Enrichment Test

Authors: A. Youn, E. J. Marquez, N. Lawlor, M. L. Stitzel, and D. Ucar


Diabetes, 2018. Type 2 Diabetes Associated Genetic Variants Regulate Chromatin Accessibility in Human Islets

Authors: S. Khetan, R. Kursawe, A. Jillette, A. Youn, N. Lawlor, E. J. Marquez, D. Ucar, and M. L. Stitzel


American Journal of Human Genetics, 2018. A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression

Authors: I. Kycia, B.N. Wolford, J.R. Huyghe, C. Fuchsberger, S. Vadlamudi, R. Kursawe, R.P. Welch, R.D. Albanus, A. Uyar, S. Khetan, N. Lawlor, M. Bolisetty, A. Mathur, J. Kuusisto, M. Laakso, D. Ucar, K.L. Mohlke, M. Boehnke, F.S. Collins, S.C.J. Parker, M.L. Stitzel


Scientific Reports, 2017. Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts

Authors: N. Lawlor(1), A. Youn (1), R. Kursawe, D. Ucar, and M. L. Stitzel (1: equal contributor)


Trends in Genetics, 2017. Genomics of Islet (Dys)function and Type 2 Diabetes

Authors: N. Lawlor, S. Khetan, D. Ucar, and M. L. Stitzel


Genome Research, 2017. Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes

Authors: N. Lawlor(1), J. George (1), M. Bolisetty, R. Kursawe, L. Sun, Sivakamasundari V, I. Kycia, P. Robson, and M. L. Stitzel (1: equal contributor)


Cancer Informatics, 2016. multiClust: An R-package for Identifying Biologically Relevant Clusters in Cancer Transcriptome Profiles

Authors: N. Lawlor (1), A. Fabbri (1), P. Guan, J. George, and R. Krishna Murthy Karuturi (1: equal contributor)


Advances in Nutrition, 2016. Human Milk Components Modulate Toll-Like Receptor-Mediated Inflammation

Authors: Y. He, N. Lawlor, and D. S. Newburg


Gut, 2016. The human milk oligosaccharide 2’-fucosyllactose modulates CD14 expression in human enterocytes, thereby attenuating LPS-induced inflammation

Authors: Y. He, S. Liu, D.E. Kling, S. Leone, N. Lawlor, Y. Huang, S.B. Feinberg, D.R. Hill, and D.S. Newburg